PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G11020.1
Common NameDREB2, DREB2B, ERF044, F9F8.16
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 330aa    MW: 37117 Da    PI: 4.7718
Description DRE/CRT-binding protein 2B
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G11020.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP256.37.9e-1876126155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  + ++GVr++  +g+WvAeIr+p++    +r +lg+f tae+Aa a+++a+ +++g
  AT3G11020.1  76 CSFRGVRQRI-WGKWVAEIREPKI---GTRLWLGTFPTAEKAASAYDEAATAMYG 126
                  579****998.**********954...3**********************99987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000187.89E-3476136No hitNo description
PfamPF008473.5E-1276126IPR001471AP2/ERF domain
PROSITE profilePS5103221.62877134IPR001471AP2/ERF domain
SMARTSM003804.0E-4077140IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.9E-3077136IPR001471AP2/ERF domain
PRINTSPR003671.5E-97889IPR001471AP2/ERF domain
SuperFamilySSF541715.56E-2078136IPR016177DNA-binding domain
PRINTSPR003671.5E-9100116IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009555Biological Processpollen development
GO:0010286Biological Processheat acclimation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000084anatomyplant sperm cell
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001016developmental stageL mature pollen stage
PO:0001017developmental stageM germinated pollen stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 330 aa     Download sequence    Send to blast
MAVYEQTGTE QPKKRKSRAR AGGLTVADRL KKWKEYNEIV EASAVKEGEK PKRKVPAKGS  60
KKGCMKGKGG PDNSHCSFRG VRQRIWGKWV AEIREPKIGT RLWLGTFPTA EKAASAYDEA  120
ATAMYGSLAR LNFPQSVGSE FTSTSSQSEV CTVENKAVVC GDVCVKHEDT DCESNPFSQI  180
LDVREESCGT RPDSCTVGHQ DMNSSLNYDL LLEFEQQYWG QVLQEKEKPK QEEEEIQQQQ  240
QEQQQQQLQP DLLTVADYGW PWSNDIVNDQ TSWDPNECFD INELLGDLNE PGPHQSQDQN  300
HVNSGSYDLH PLHLEPHDGH EFNGLSSLDI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A7e-1978137363ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
3gcc_A8e-1978139668ATERF1
2gcc_A8e-1978139668ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.2340.0seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible256430_at0.0
Expression AtlasAT3G11020-
AtGenExpressAT3G11020-
ATTED-IIAT3G11020-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed preferentially in roots and stems, and at a lower level in leaves. {ECO:0000269|PubMed:10809011}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family (DREB2B). The protein contains one AP2 domain. There are eight members in this subfamily including DREB2A.
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. {ECO:0000269|PubMed:11798174}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00346DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G11020.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high-salt and drought stresses. {ECO:0000269|PubMed:10809011, ECO:0000269|PubMed:9707537}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
IntActSearch O82133
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G11020
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0077910.0AB007791.1 Arabidopsis thaliana mRNA for DREB2B, complete cds.
GenBankAB0165710.0AB016571.1 Arabidopsis thaliana DREB2B gene, complete cds.
GenBankAK1173630.0AK117363.1 Arabidopsis thaliana At3g11020 mRNA for putative DREB2B transcription factor, complete cds, clone: RAFL16-93-F04.
GenBankATAC0099910.0AC009991.5 Arabidopsis thaliana chromosome III BAC F9F8 genomic sequence, complete sequence.
GenBankBT0083510.0BT008351.1 Arabidopsis thaliana At3g11020 mRNA, complete cds.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
GenBankKC4122530.0KC412253.1 Arabidopsis thaliana DRE/CRT-binding protein 2B (DREB2B) mRNA, DREB2B-AT3G11020 allele, complete cds, alternatively spliced.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_187713.10.0dehydration-responsive element-binding protein 2B
SwissprotO821330.0DRE2B_ARATH; Dehydration-responsive element-binding protein 2B
TrEMBLM4VR860.0M4VR86_ARATH; DRE/CRT-binding protein 2B
STRINGAT3G11020.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM28741765
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Nakashima K, et al.
    Organization and expression of two Arabidopsis DREB2 genes encoding DRE-binding proteins involved in dehydration- and high-salinity-responsive gene expression.
    Plant Mol. Biol., 2000. 42(4): p. 657-65
    [PMID:10809011]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Sakuma Y, et al.
    DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression.
    Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009
    [PMID:11798174]
  4. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  5. Hao D,Yamasaki K,Sarai A,Ohme-Takagi M
    Determinants in the sequence specific binding of two plant transcription factors, CBF1 and NtERF2, to the DRE and GCC motifs.
    Biochemistry, 2002. 41(13): p. 4202-8
    [PMID:11914065]
  6. Boyce JM, et al.
    The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress.
    Plant J., 2003. 34(4): p. 395-406
    [PMID:12753580]
  7. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  8. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  9. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  10. Egawa C, et al.
    Differential regulation of transcript accumulation and alternative splicing of a DREB2 homolog under abiotic stress conditions in common wheat.
    Genes Genet. Syst., 2006. 81(2): p. 77-91
    [PMID:16755132]
  11. Lim CJ, et al.
    Gene expression profiles during heat acclimation in Arabidopsis thaliana suspension-culture cells.
    J. Plant Res., 2006. 119(4): p. 373-83
    [PMID:16807682]
  12. Qin F, et al.
    Regulation and functional analysis of ZmDREB2A in response to drought and heat stresses in Zea mays L.
    Plant J., 2007. 50(1): p. 54-69
    [PMID:17346263]
  13. Schramm F, et al.
    A cascade of transcription factor DREB2A and heat stress transcription factor HsfA3 regulates the heat stress response of Arabidopsis.
    Plant J., 2008. 53(2): p. 264-74
    [PMID:17999647]
  14. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  15. Jaspers P, et al.
    Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors.
    Plant J., 2009. 60(2): p. 268-79
    [PMID:19548978]
  16. Brady SM, et al.
    A stele-enriched gene regulatory network in the Arabidopsis root.
    Mol. Syst. Biol., 2011. 7: p. 459
    [PMID:21245844]
  17. Reňák D,Dupl'áková N,Honys D
    Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis.
    Sex. Plant Reprod., 2012. 25(1): p. 39-60
    [PMID:22101548]
  18. Vainonen JP, et al.
    RCD1-DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana.
    Biochem. J., 2012. 442(3): p. 573-81
    [PMID:22150398]
  19. Zhao K, et al.
    Isolation and characterization of dehydration-responsive element-binding factor 2C (MsDREB2C) from Malus sieversii Roem.
    Plant Cell Physiol., 2013. 54(9): p. 1415-30
    [PMID:23757363]
  20. Liu Q, et al.
    Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis.
    Plant Cell, 1998. 10(8): p. 1391-406
    [PMID:9707537]